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| Product Name: |
Doxofylline
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| Supply Ability: |
150T |
| Related proudcts |
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| Specifications |
99.0% |
| Price Term: |
FOB |
| Port of loading: |
Shang Hai |
| Minimum Order |
50KG |
| Unit Price: |
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Main ingredients of this product are: Doxofylline. Its chemical name: 1,3 - dimethyl -7 - (1,3 - dioxo-cyclopentyl -2 - yl) methyl -3,7 - dihydro-1H-purine -2,6 - dione .
¡¾Properties¡¿
This product is colorless clear liquid.
¡¾Pharmacology and toxicology¡¿
Doxofylline is a derivative of methylxanthine, it is a bronchodilator can directly act on the bronchus, bronchial smooth muscle relaxation. Within the smooth muscle cells by inhibiting phosphodiesterase and so the role of smooth muscle relaxation to achieve the inhibitory effects of asthma.
Pharmacokinetics¡¿
Intravenous injection in patients with chronic bronchitis Doxofylline 100mg (injection of more than 10 minutes), after administration of drug in plasma peak time (***x) is approximately 0.10 hours, peak plasma concentration (Cmax) of about 2.50¦Ìg/ml, elimination half-life (t1 / 2) is about 1.83 hours, can rapidly distributed to various body fluids and organs, with a total clearance rate (683.6 ¡À 197.8) ml / min. Consumption can peak concentration (Cmax) decreased peak time (***x) delay, should increase the dose.
¡¾Indications¡¿
Bronchial asthma, wheeze and chronic bronchitis and other breathing difficulties caused by bronchial ***sms.
¡¾Usage consumption¡¿
Adults per 200mg, 12 hours with a 25% glucose injection was diluted to 40ml slow intravenous injection, time should be within 20 minutes, 5 to 10 day course of treatment or a ***tor's advice. This product can also be 300mg in 5% glucose injection or saline injection 100ml in a slow intravenous infusion once a day.
Adverse reactions ¡¾¡¿
The use of xanthine derivatives may cause nausea, vomiting, upper abdominal pain, headache, insomnia, irritability, tachycardia, premature beat, shortness of breath, high blood glucose, proteinuria. Such as excessive use will be a serious cardiac arrhythmia, paroxysmal convulsions. This showed the initial symptoms of poisoning, this time should be suspended medication, a ***tor diagnosis, monitoring of blood drug concentra |
| Company: |
Anhui Langxi Lianke Industrial Co.,Ltd
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| Contact: |
Mr. Ting Zhou |
| Address: |
49#,Shangjiaodi, Langxi, China |
| Postcode: |
242100 |
| Tel: |
86-563-7087075 |
| Fax: |
86-563-7086516 |
| E-mail: |
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